Other than that, bring the items you like and which are good for defense, such as Shield Vials. Other key items are Large Silphium Vials, which can heal you in a pinch, and Damage Siphons, which allow you to convert the damage you do to the boss into health for yourself. If you can find one, the Astronaut Figure and Child’s Watch artifacts are great they’ll instantly bring you back to life mid-fight if you die, which is even better than the Recombinator, since you won’t have to restart the fight from the beginning. In addition to the Recombinator, prioritize a few key artifacts and items to bring with you. A Recombinator will give you an extra life should you die, so you’ll have a second shot at the boss. You’ll need six Ether to run them, so make sure you’ve stockpiled some. These are the large, round machines with an indentation of an alien body inside. You should also try to find and power a Recombinator in the biome you’re exploring. These boss fights are battles of attrition where sustained damage is the most important thing, so bring something you can use well to do a lot of damage quickly. It’s a good idea to prioritize having a gun you like and are comfortable with over one with the highest stats you can find, however. It’s always a good idea to find as much Silphium Resin as you can to increase your health before a boss fight, and to bring a hard-hitting gun with you as well. You’ll usually need to unlock the boss chamber as you work through each new biome, but once you’ve opened it, it’ll stay open–you can just sprint straight to the boss on later runs. First and foremost, you’ll want to prep for every boss fight well before you take it on.
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